The purpose of this project is to study the fluorescent properties and photochemistry of thiazolothiazole viologens for solar energy applications. In particular we will study the photoinduced electron transfer events from a donor chromophore to an acceptor thiazolothiazole viologen (TTz). We will monitor these dynamics by studying the fluorescence both of the donor and acceptor molecules.
The overall objective of this project is to identify the design rules for fabricating organized gold nanoclusters that have the desired chemical, physical, and optical properties for cancer theranostics, but can also undergo controlled disassembly in vivo to facilitate their complete clearance from the body to ensure their safe application.
Despite the existing variety of RNA (and DNA) nanoparticles (NPs) and computational tools for their design, the use of RNA NPs as modular building blocks for constructing RNA networks has never been systematically investigated. To address this need and thereby shift the existing paradigm, the goal of this project is to develop an RNA-based, programmable networking platform that simultaneously encodes targeted biophysical, mechanical, and biochemical properties through networks with multiple independently programmable architectural parameters.